It should work in 64bit hosts using a “bitbridge”, but this is untested by the author. It may be used with any host software that can load and use VST2.4/32bit-compatible plugins, tested by the author are Cakewalk Sonar (4, 7), Sony Sound Forge (9) and DirectiXer (2.5). Is called a DeEsser because it’s mainly designed to get rid of „stinging“ sibilants that may occur on vocals after compression or adding a high boost.